Buy Methiopropamine (MPA) Online
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Buy Methiopropamine (MPA) Online
Are you Looking to Buy Methiopropamine Online for research purposes?At ChemHeaven, we supply high-purity MPA suitable for laboratory analysis, neurochemical research, and pharmacological profiling.
what is methiopropamine
Methiopropamine (usually abbreviated as MPA, also called N-methylthiopropamine, methiopropamine, or 1-(thiophen-2-yl)-2-methylaminopropane) is apsychoactive substance drug that belongs to the class of novel psychoactive substances (NPS). It can be considered an analog of the drug methamphetamine (crystal meth), with the difference being the replacement of the benzene ring with a thiophene ring. The chemical formula of the drug is given as C8H13NS
methiopropamine uses
Methiopropamine (MPA) has no medical, therapeutic, or legitimate use in any country as of February 26, 2026. It is a synthetic stimulant classified as a novel psychoactive substance (NPS) and a psychoactive substance (Schedule I in the US, Class B in the UK, and prohibited in the rest of the world).
Primary (Illicit/Recreational) Use
Recreational use of the drug as a stimulant for its central nervous system effects. Users report the following:
Increased levels of energy, alertness, and focus.
Stimulation with less fatigue (often called a “functional stimulant” like caffeine or methylphenidate/Ritalin).
Mild mental stimulation with less euphoric effects than methamphetamine/amphetamines, making it attractive for studying, working late, or productivity (very subjective).
Common methods of use: insufflation (snorted), vaporization/inhaling, oral consumption (not very effective), and rarely IV/rectal routes.
how to make methiopropamine
Methiopropamine (MPA) = 1-(thiophen-2-yl)-2-methylaminopropane. Essentially methamphetamine with the benzene ring replaced with the thiophene ring. There are two main synthesis routes that individuals have used in real-world labs.
Route 1 – Via 2-thiophen-1
1)-Starting material
Thiophene + propionyl chloride + AlCl₃ (Friedel-Crafts acylation)
1-(thiophen-2-yl)propan-1-one (2-propionylthiophene)
Quantities
84 g thiophene
93 g propionyl chloride
133 g anhydrous AlCl₃
Solvent: carbon disulfide or DCM
Reflux 2-3 hours after adding slowly at 0-5°C.
Hydrolyze, extract, distill.
Yield: 70-85%
2)-Alpha-bromination
Ketone + Br₂ in glacial acetic acid or chloroform
2-bromo-1-(thiophen-2-yl)propan-1-one
Bromine adds to alpha carbon, NOT the ring
3)=Amination
Bromoketone + excess methylamine (40% aq or gas in methanol) → imine
Reduce immediately:
NaBH4/methanol
or
Al/Hg amalgam (classic method)
→ racemic methiopropamine freebase
Alternative: direct reductive amination of the ketone with MeNH2 + NaBH3CN or NaBH(OAc)3/methanol.
Workup & salt
Extract base with non-polar solvent; dry; bubble dry HCl gas or add HCl/IPA → hydrochloride salt (white brittle crystals; hygroscopic; mp 170–180 °C).
| Weight | 10 Grams, 1000 Grams, 250 Grams, 50 Grams, 500 Grams |
|---|
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